Full-pipeline results
Plots for each diversity
Effect sizes (Two-group comparison)
Taxonomy
KEGG Orthology
KEGG Pathway
Comparison of Taxonomy
| coef (non-PD) | pval | qval | |
|---|---|---|---|
| Lachnospiraceae_ND3007_group;__ | -0.709 | 0.001 | 0.089 |
| Erysipelotrichaceae_UCG003;__ | -0.601 | 0.003 | 0.215 |
| Lachnospiraceae;uncultured;uncultured_Eubacterium | -0.175 | 0.005 | 0.217 |
| Butyricicoccus;__ | -0.469 | 0.005 | 0.217 |
| Christensenellaceae_R7_group;uncultured_prokaryote | -0.508 | 0.009 | 0.245 |
| Anaerostipes;__ | -0.574 | 0.009 | 0.245 |
| Faecalibacterium;__ | -0.535 | 0.014 | 0.321 |
| Rhodospirillales;uncultured;uncultured;gut_metagenome | 0.598 | 0.017 | 0.354 |
| Collinsella;__ | 0.452 | 0.036 | 0.421 |
| Coprococcus;__ | -0.506 | 0.029 | 0.421 |
| GCA900066575;__ | -0.255 | 0.035 | 0.421 |
| Ruminococcus_gauvreauii_group;__ | -0.287 | 0.039 | 0.421 |
| Monoglobus;__ | -0.518 | 0.027 | 0.421 |
| Fusobacterium;__ | 0.345 | 0.028 | 0.421 |
| Pasteurellaceae;__;__ | 0.438 | 0.037 | 0.421 |
| Lachnospira;__ | -0.679 | 0.048 | 0.485 |
| UCG010;__ | -0.237 | 0.055 | 0.502 |
| Eubacterium_coprostanoligenes_group;unidentified | 0.398 | 0.054 | 0.502 |
| Intestinimonas_butyriciproducens | 0.266 | 0.059 | 0.510 |
| Eubacterium_eligens_group;__ | -0.526 | 0.066 | 0.537 |
| Alistipes_finegoldii | -0.322 | 0.086 | 0.566 |
| Clostridium_spiroforme | -0.254 | 0.101 | 0.566 |
| Dielma;__ | 0.156 | 0.096 | 0.566 |
| Eubacterium_ramulus | -0.249 | 0.083 | 0.566 |
| Lachnospiraceae_UCG010;uncultured_organism | -0.154 | 0.099 | 0.566 |
| Intestinimonas;__ | 0.154 | 0.093 | 0.566 |
| Oscillospiraceae;uncultured;uncultured_rumen | 0.091 | 0.078 | 0.566 |
| Clostridium_methylpentosum_group;__ | -0.112 | 0.076 | 0.566 |
| EscherichiaShigella;__ | 0.635 | 0.090 | 0.566 |
| Eubacterium_coprostanoligenes_group;__ | -0.399 | 0.120 | 0.653 |
| Parabacteroides_merdae | 0.244 | 0.133 | 0.701 |
| Muribaculaceae;uncultured_Bacteroidales | 0.154 | 0.162 | 0.716 |
| Candidatus_Stoquefichus;__ | 0.329 | 0.146 | 0.716 |
| UCG005;__ | -0.335 | 0.141 | 0.716 |
| Hydrogenoanaerobacterium;__ | 0.160 | 0.163 | 0.716 |
| DTU089;__ | 0.298 | 0.150 | 0.716 |
| Cloacibacillus_evryensis | 0.226 | 0.161 | 0.716 |
| Desulfovibrio;__ | 0.285 | 0.171 | 0.734 |
| Holdemania;__ | -0.238 | 0.178 | 0.744 |
| Alistipes;__ | -0.293 | 0.216 | 0.745 |
| Erysipelatoclostridium;__ | 0.311 | 0.199 | 0.745 |
| Faecalitalea;__ | 0.218 | 0.211 | 0.745 |
| Clostridia;__;__;__;__ | 0.191 | 0.219 | 0.745 |
| Lachnospiraceae;__;__ | -0.235 | 0.194 | 0.745 |
| Clostridium_scindens | 0.119 | 0.203 | 0.745 |
| UCG002;uncultured_rumen | -0.240 | 0.210 | 0.745 |
| Ruminococcus_bicirculans | -0.258 | 0.196 | 0.745 |
| Azospirillum_sp | 0.176 | 0.213 | 0.745 |
| Eubacterium_xylanophilum_group;uncultured_organism | -0.203 | 0.227 | 0.756 |
| Alistipes_sp | -0.217 | 0.255 | 0.778 |
| Angelakisella;uncultured_bacterium | 0.109 | 0.242 | 0.778 |
| Eubacterium_siraeum_group;__ | -0.341 | 0.248 | 0.778 |
| Family_XIII_AD3011_group;uncultured_organism | -0.090 | 0.256 | 0.778 |
| Veillonella;__ | 0.308 | 0.258 | 0.778 |
| Agathobacter;__ | -0.256 | 0.268 | 0.795 |
| Eubacterium_hallii_group;__ | 0.235 | 0.274 | 0.797 |
| UBA1819;__ | 0.253 | 0.294 | 0.840 |
| Coriobacteriales;Coriobacteriales_Incertae_Sedis;uncultured;gut_metagenome | -0.104 | 0.325 | 0.859 |
| Bacteroides;__ | -0.100 | 0.389 | 0.859 |
| Bacteroides_eggerthii | 0.120 | 0.387 | 0.859 |
| Barnesiella;__ | 0.108 | 0.383 | 0.859 |
| Odoribacter_splanchnicus | 0.117 | 0.385 | 0.859 |
| Paraprevotella;__ | -0.144 | 0.420 | 0.859 |
| Alistipes_obesi | -0.110 | 0.427 | 0.859 |
| Blautia_hydrogenotrophica | -0.079 | 0.369 | 0.859 |
| Eisenbergiella;__ | 0.137 | 0.419 | 0.859 |
| Fusicatenibacter;__ | -0.170 | 0.368 | 0.859 |
| Lachnospiraceae_UCG004;__ | -0.111 | 0.373 | 0.859 |
| Roseburia;__ | -0.229 | 0.310 | 0.859 |
| Eubacterium_ventriosum_group;uncultured_Lachnospiraceae | -0.114 | 0.337 | 0.859 |
| Eubacterium_ventriosum_group;uncultured_bacterium | 0.069 | 0.417 | 0.859 |
| Eubacterium_xylanophilum_group;__ | 0.111 | 0.328 | 0.859 |
| UCG005;uncultured_organism | -0.166 | 0.356 | 0.859 |
| Ruminococcaceae;__;__ | -0.240 | 0.416 | 0.859 |
| Anaerotruncus_sp | 0.140 | 0.425 | 0.859 |
| Clostridium_leptum | 0.167 | 0.356 | 0.859 |
| Ruminococcus;__ | -0.197 | 0.405 | 0.859 |
| Anaerovoracaceae;__;__ | -0.161 | 0.416 | 0.859 |
| Eubacterium_brachy_group;uncultured_bacterium | -0.082 | 0.383 | 0.859 |
| Eubacterium_nodatum_group;unidentified | 0.122 | 0.337 | 0.859 |
| Enterobacteriaceae;__;__ | 0.213 | 0.357 | 0.859 |
| Methanobrevibacter;__ | 0.062 | 0.569 | 0.859 |
| Bifidobacterium;__ | 0.154 | 0.563 | 0.859 |
| Bacteroides_massiliensis | -0.081 | 0.474 | 0.859 |
| Muribaculaceae;uncultured_bacterium | 0.086 | 0.448 | 0.859 |
| Acinetobacter_sp | -0.054 | 0.469 | 0.859 |
| Firmicutes;__;__;__;__;__ | 0.048 | 0.459 | 0.859 |
| Holdemania;uncultured_bacterium | -0.036 | 0.554 | 0.859 |
| Clostridium_innocuum_group;__ | -0.106 | 0.539 | 0.859 |
| Streptococcus;__ | 0.199 | 0.490 | 0.859 |
| Christensenellaceae_R7_group;__ | 0.155 | 0.548 | 0.859 |
| Christensenellaceae_R7_group;uncultured_marine | 0.062 | 0.446 | 0.859 |
| Clostridia_vadinBB60_group;gut_metagenome | -0.095 | 0.461 | 0.859 |
| Clostridium_sensu_stricto_1;__ | 0.087 | 0.547 | 0.859 |
| Dorea;__ | -0.169 | 0.543 | 0.859 |
| Hungatella;__ | -0.090 | 0.515 | 0.859 |
| Lachnospiraceae_NK4A136_group;__ | -0.168 | 0.563 | 0.859 |
| Sellimonas;uncultured_bacterium | 0.097 | 0.529 | 0.859 |
| Oscillospirales;__;__;__ | 0.075 | 0.493 | 0.859 |
| Oscillospiraceae;__;__ | 0.140 | 0.508 | 0.859 |
| Colidextribacter;uncultured_Clostridia | 0.099 | 0.568 | 0.859 |
| Anaerotruncus;__ | 0.093 | 0.491 | 0.859 |
| Subdoligranulum;__ | -0.193 | 0.520 | 0.859 |
| Ruminococcaceae;uncultured;__ | 0.053 | 0.558 | 0.859 |
| Ruminococcaceae;uncultured;human_gut | 0.081 | 0.458 | 0.859 |
| Family_XIII_AD3011_group;__ | 0.116 | 0.532 | 0.859 |
| Akkermansia;__ | -0.227 | 0.494 | 0.859 |
| Akkermansia_muciniphila | 0.331 | 0.434 | 0.859 |
| Eggerthellaceae;uncultured;__ | -0.055 | 0.581 | 0.869 |
| Romboutsia;__ | -0.142 | 0.587 | 0.869 |
| Clostridia_vadinBB60_group;uncultured_organism | -0.049 | 0.598 | 0.878 |
| Eggerthella;__ | 0.049 | 0.641 | 0.902 |
| Alistipes_indistinctus | -0.048 | 0.626 | 0.902 |
| Parabacteroides_goldsteinii | -0.060 | 0.642 | 0.902 |
| Bilophila;__ | -0.176 | 0.631 | 0.902 |
| Peptococcus;uncultured_organism | -0.059 | 0.632 | 0.902 |
| Butyricimonas;__ | 0.116 | 0.652 | 0.908 |
| Turicibacter;__ | -0.026 | 0.682 | 0.917 |
| Eubacterium_ruminantium_group;uncultured_bacterium | 0.028 | 0.675 | 0.917 |
| Ruminococcus_torques_group;__ | -0.090 | 0.686 | 0.917 |
| NK4A214_group;__ | -0.076 | 0.686 | 0.917 |
| UCG002;uncultured_organism | 0.091 | 0.685 | 0.917 |
| Ruminococcus_gnavus_group;__ | 0.104 | 0.694 | 0.920 |
| Bacteroides_stercoris | 0.096 | 0.701 | 0.922 |
| Clostridia_vadinBB60_group;uncultured_bacterium | 0.071 | 0.711 | 0.922 |
| Ruminococcaceae;Incertae_Sedis;uncultured_organism | -0.053 | 0.713 | 0.922 |
| Flavonifractor;__ | 0.075 | 0.726 | 0.931 |
| Roseburia;gut_metagenome | 0.053 | 0.740 | 0.942 |
| Adlercreutzia;__ | -0.042 | 0.767 | 0.943 |
| Massiliomicrobiota_timonensis | -0.038 | 0.816 | 0.943 |
| Izemoplasmatales;uncultured_organism | -0.033 | 0.747 | 0.943 |
| Lactobacillus;__ | 0.026 | 0.805 | 0.943 |
| Clostridia_vadinBB60_group;uncultured_Thermoanaerobacterales | -0.033 | 0.767 | 0.943 |
| Blautia;__ | -0.031 | 0.805 | 0.943 |
| Frisingicoccus;__ | -0.045 | 0.803 | 0.943 |
| Lachnospiraceae_UCG001;__ | -0.040 | 0.792 | 0.943 |
| Anaerotignum_lactatifermentans | -0.057 | 0.795 | 0.943 |
| NK4A214_group;metagenome | -0.019 | 0.815 | 0.943 |
| UCG003;__ | 0.031 | 0.775 | 0.943 |
| Acidaminococcus;__ | -0.044 | 0.811 | 0.943 |
| Sutterella;__ | 0.031 | 0.789 | 0.943 |
| Oscillospiraceae;uncultured;__ | -0.024 | 0.837 | 0.961 |
| Parabacteroides;__ | 0.039 | 0.867 | 0.984 |
| Eubacterium_ventriosum_group;__ | 0.016 | 0.869 | 0.984 |
| CAG56;uncultured_bacterium | 0.014 | 0.911 | 0.990 |
| Oscillibacter;__ | 0.024 | 0.898 | 0.990 |
| Ruminococcaceae;Incertae_Sedis;__ | 0.036 | 0.889 | 0.990 |
| Peptococcaceae;uncultured;unidentified | 0.013 | 0.905 | 0.990 |
| Dialister;__ | 0.033 | 0.909 | 0.990 |
| Parasutterella;__ | 0.031 | 0.902 | 0.990 |
| Coprobacter;__ | -0.009 | 0.965 | 0.994 |
| Christensenellaceae;uncultured;uncultured_bacterium | 0.004 | 0.962 | 0.994 |
| Clostridia_UCG014;__ | -0.005 | 0.988 | 0.994 |
| Lachnoclostridium;__ | -0.008 | 0.968 | 0.994 |
| Colidextribacter;__ | 0.016 | 0.934 | 0.994 |
| UCG002;__ | -0.005 | 0.984 | 0.994 |
| CAG352;uncultured_bacterium | 0.012 | 0.929 | 0.994 |
| Negativibacillus;__ | 0.021 | 0.926 | 0.994 |
| Paludicola;uncultured_bacterium | -0.001 | 0.986 | 0.994 |
| Family_XIII_UCG001;uncultured_bacterium | 0.002 | 0.985 | 0.994 |
| Intestinibacter;__ | 0.009 | 0.966 | 0.994 |
| Phascolarctobacterium;__ | 0.005 | 0.987 | 0.994 |
| Clostridium_sp | 0.000 | 0.997 | 0.997 |
Comparison of Taxonomy
Comparison of Taxonomy
| coef (non-PD) | pval | qval | |
|---|---|---|---|
| Lachnospiraceae_ND3007_group | -0.693 | 0.001 | 0.078 |
| Erysipelotrichaceae_UCG003 | -0.597 | 0.003 | 0.165 |
| Rhodospirillales;uncultured;uncultured | 0.734 | 0.004 | 0.177 |
| Butyricicoccus | -0.456 | 0.006 | 0.189 |
| Anaerostipes | -0.570 | 0.009 | 0.218 |
| Faecalibacterium | -0.526 | 0.015 | 0.303 |
| Collinsella | 0.459 | 0.034 | 0.315 |
| Muribaculaceae | 0.380 | 0.026 | 0.315 |
| Coprococcus | -0.498 | 0.035 | 0.315 |
| GCA900066575 | -0.475 | 0.023 | 0.315 |
| Monoglobus | -0.499 | 0.034 | 0.315 |
| Intestinimonas | 0.336 | 0.022 | 0.315 |
| Fusobacterium | 0.346 | 0.027 | 0.315 |
| Pasteurellaceae;__ | 0.439 | 0.036 | 0.315 |
| Lachnospira | -0.673 | 0.049 | 0.378 |
| Ruminococcus_gauvreauii_group | -0.274 | 0.048 | 0.378 |
| Eubacterium_eligens_group | -0.519 | 0.068 | 0.490 |
| UCG010 | -0.386 | 0.076 | 0.519 |
| Clostridium_methylpentosum_group | -0.111 | 0.080 | 0.520 |
| Dielma | 0.156 | 0.098 | 0.557 |
| Oscillospiraceae;uncultured | 0.349 | 0.091 | 0.557 |
| EscherichiaShigella | 0.647 | 0.100 | 0.557 |
| Candidatus_Stoquefichus | 0.365 | 0.110 | 0.579 |
| Cloacibacillus | 0.264 | 0.113 | 0.579 |
| Holdemania | -0.305 | 0.121 | 0.597 |
| Alistipes | -0.346 | 0.141 | 0.642 |
| Lachnospiraceae;uncultured | -0.166 | 0.137 | 0.642 |
| DTU089 | 0.291 | 0.152 | 0.670 |
| Hydrogenoanaerobacterium | 0.159 | 0.164 | 0.697 |
| Coriobacteriales;Coriobacteriales_Incertae_Sedis;uncultured | -0.136 | 0.219 | 0.709 |
| Faecalitalea | 0.245 | 0.215 | 0.709 |
| Clostridia;__;__;__ | 0.193 | 0.212 | 0.709 |
| Lachnospiraceae;__ | -0.230 | 0.199 | 0.709 |
| Agathobacter | -0.310 | 0.214 | 0.709 |
| Lachnospiraceae_UCG010 | -0.127 | 0.206 | 0.709 |
| UCG005 | -0.323 | 0.211 | 0.709 |
| Anaerotruncus | 0.278 | 0.213 | 0.709 |
| Ruminococcus | -0.362 | 0.214 | 0.709 |
| Angelakisella | 0.112 | 0.238 | 0.750 |
| Lachnospiraceae_NK4A136_group | -0.337 | 0.244 | 0.751 |
| Paraprevotella | -0.197 | 0.258 | 0.761 |
| Veillonella | 0.306 | 0.260 | 0.761 |
| Parabacteroides | 0.132 | 0.277 | 0.792 |
| Odoribacter | 0.163 | 0.288 | 0.794 |
| UBA1819 | 0.273 | 0.291 | 0.794 |
| Eubacterium_nodatum_group | 0.169 | 0.301 | 0.805 |
| Barnesiella | 0.112 | 0.373 | 0.855 |
| Desulfovibrio | 0.204 | 0.369 | 0.855 |
| Streptococcus | 0.247 | 0.396 | 0.855 |
| Clostridia_vadinBB60_group | -0.218 | 0.383 | 0.855 |
| Fusicatenibacter | -0.166 | 0.377 | 0.855 |
| Lachnospiraceae_UCG004 | -0.104 | 0.396 | 0.855 |
| Roseburia | -0.185 | 0.396 | 0.855 |
| Eubacterium_hallii_group | 0.187 | 0.367 | 0.855 |
| Ruminococcaceae;__ | -0.265 | 0.396 | 0.855 |
| Eubacterium_siraeum_group | -0.279 | 0.346 | 0.855 |
| Enterobacteriaceae;__ | 0.221 | 0.339 | 0.855 |
| Methanobrevibacter | 0.062 | 0.572 | 0.883 |
| Bifidobacterium | 0.157 | 0.575 | 0.883 |
| Eggerthellaceae;uncultured | -0.056 | 0.582 | 0.883 |
| Bacteroides | -0.086 | 0.462 | 0.883 |
| Firmicutes;__;__;__;__ | 0.048 | 0.462 | 0.883 |
| Clostridium_innocuum_group | -0.100 | 0.553 | 0.883 |
| Christensenellaceae_R7_group | -0.228 | 0.429 | 0.883 |
| Clostridium_sensu_stricto_1 | 0.105 | 0.487 | 0.883 |
| Dorea | -0.160 | 0.565 | 0.883 |
| Eisenbergiella | 0.137 | 0.421 | 0.883 |
| Hungatella | -0.094 | 0.491 | 0.883 |
| Sellimonas | 0.110 | 0.512 | 0.883 |
| Eubacterium_xylanophilum_group | -0.143 | 0.476 | 0.883 |
| Oscillospirales;__;__ | 0.077 | 0.479 | 0.883 |
| Oscillospiraceae;__ | 0.144 | 0.491 | 0.883 |
| NK4A214_group | -0.149 | 0.489 | 0.883 |
| UCG002 | -0.182 | 0.519 | 0.883 |
| Ruminococcaceae;Incertae_Sedis | 0.136 | 0.563 | 0.883 |
| Paludicola | -0.047 | 0.533 | 0.883 |
| Subdoligranulum | -0.169 | 0.571 | 0.883 |
| Ruminococcaceae;uncultured | 0.102 | 0.541 | 0.883 |
| Anaerovoracaceae;__ | -0.154 | 0.434 | 0.883 |
| Eubacterium_brachy_group | -0.054 | 0.571 | 0.883 |
| Romboutsia | -0.143 | 0.581 | 0.883 |
| Bilophila | -0.176 | 0.630 | 0.900 |
| Lachnospiraceae_UCG001 | -0.078 | 0.629 | 0.900 |
| Tyzzerella | 0.093 | 0.627 | 0.900 |
| Family_XIII_AD3011_group | 0.099 | 0.612 | 0.900 |
| Parasutterella | 0.128 | 0.603 | 0.900 |
| Eggerthella | 0.046 | 0.659 | 0.901 |
| Turicibacter | -0.029 | 0.641 | 0.901 |
| Eubacterium_ruminantium_group | 0.030 | 0.645 | 0.901 |
| Ruminococcus_torques_group | -0.100 | 0.657 | 0.901 |
| Christensenellaceae;uncultured | 0.052 | 0.673 | 0.901 |
| Lachnoclostridium | 0.094 | 0.674 | 0.901 |
| Sutterella | 0.047 | 0.685 | 0.906 |
| Adlercreutzia | -0.043 | 0.762 | 0.910 |
| Prevotella | 0.089 | 0.739 | 0.910 |
| Gastranaerophilales | -0.064 | 0.738 | 0.910 |
| Erysipelatoclostridium | 0.111 | 0.727 | 0.910 |
| Izemoplasmatales | -0.032 | 0.752 | 0.910 |
| Ruminococcus_gnavus_group | 0.100 | 0.705 | 0.910 |
| Colidextribacter | 0.081 | 0.737 | 0.910 |
| Flavonifractor | 0.076 | 0.723 | 0.910 |
| Fournierella | -0.031 | 0.762 | 0.910 |
| Peptococcaceae;uncultured | 0.042 | 0.744 | 0.910 |
| Butyricimonas | 0.055 | 0.828 | 0.927 |
| Lactobacillus | 0.037 | 0.786 | 0.927 |
| Blautia | -0.026 | 0.829 | 0.927 |
| Frisingicoccus | -0.043 | 0.809 | 0.927 |
| Oscillibacter | -0.047 | 0.799 | 0.927 |
| Dialister | 0.069 | 0.814 | 0.927 |
| Akkermansia | -0.107 | 0.815 | 0.927 |
| Eubacterium_coprostanoligenes_group | -0.042 | 0.848 | 0.931 |
| Acidaminococcus | -0.036 | 0.842 | 0.931 |
| UCG003 | 0.019 | 0.870 | 0.947 |
| Negativibacillus | 0.030 | 0.897 | 0.968 |
| CAG56 | 0.012 | 0.928 | 0.991 |
| Intestinibacter | 0.018 | 0.935 | 0.991 |
| Coprobacter | 0.001 | 0.995 | 0.999 |
| Clostridia_UCG014 | 0.000 | 0.999 | 0.999 |
| Eubacterium_ventriosum_group | -0.003 | 0.984 | 0.999 |
| CAG352 | 0.006 | 0.965 | 0.999 |
| Peptococcus | 0.003 | 0.989 | 0.999 |
| Family_XIII_UCG001 | 0.006 | 0.957 | 0.999 |
| Phascolarctobacterium | 0.001 | 0.999 | 0.999 |
Comparison of Taxonomy
Comparison of Taxonomy
| coef (non-PD) | pval | qval | |
|---|---|---|---|
| Butyricicoccaceae | -0.526 | 0.001 | 0.045 |
| Rhodospirillales;uncultured | 0.733 | 0.004 | 0.105 |
| Coriobacteriaceae | 0.462 | 0.033 | 0.246 |
| Muribaculaceae | 0.385 | 0.026 | 0.246 |
| Monoglobaceae | -0.499 | 0.034 | 0.246 |
| Fusobacteriaceae | 0.349 | 0.027 | 0.246 |
| Pasteurellaceae | 0.442 | 0.036 | 0.246 |
| Erysipelatoclostridiaceae | -0.312 | 0.086 | 0.377 |
| Lachnospiraceae | -0.144 | 0.073 | 0.377 |
| UCG010 | -0.384 | 0.076 | 0.377 |
| Clostridium_methylpentosum_group | -0.111 | 0.079 | 0.377 |
| Ruminococcaceae | -0.200 | 0.102 | 0.406 |
| Enterobacteriaceae | 0.621 | 0.121 | 0.427 |
| Synergistaceae | 0.288 | 0.125 | 0.427 |
| Rikenellaceae | -0.324 | 0.167 | 0.501 |
| Oscillospirales | 0.159 | 0.165 | 0.501 |
| Coriobacteriales;Coriobacteriales_Incertae_Sedis | -0.136 | 0.217 | 0.560 |
| Marinifilaceae | 0.214 | 0.222 | 0.560 |
| Clostridia;__;__ | 0.192 | 0.212 | 0.560 |
| Tannerellaceae | 0.133 | 0.274 | 0.657 |
| Bacteroidaceae | -0.085 | 0.467 | 0.824 |
| Firmicutes;__;__;__ | 0.051 | 0.440 | 0.824 |
| Streptococcaceae | 0.223 | 0.442 | 0.824 |
| Clostridia_vadinBB60_group | -0.217 | 0.384 | 0.824 |
| Clostridiaceae | 0.107 | 0.476 | 0.824 |
| Oscillospirales;__ | 0.077 | 0.481 | 0.824 |
| Veillonellaceae | 0.343 | 0.399 | 0.824 |
| Victivallaceae | 0.062 | 0.366 | 0.824 |
| Bifidobacteriaceae | 0.176 | 0.525 | 0.840 |
| Acidaminococcaceae | -0.208 | 0.508 | 0.840 |
| Methanobacteriaceae | 0.062 | 0.573 | 0.864 |
| Christensenellaceae | -0.160 | 0.576 | 0.864 |
| Desulfovibrionaceae | -0.171 | 0.617 | 0.871 |
| Sutterellaceae | 0.120 | 0.604 | 0.871 |
| Barnesiellaceae | 0.122 | 0.686 | 0.910 |
| Prevotellaceae | -0.116 | 0.771 | 0.910 |
| Gastranaerophilales | -0.063 | 0.743 | 0.910 |
| Erysipelotrichaceae | 0.080 | 0.696 | 0.910 |
| Izemoplasmatales | -0.031 | 0.761 | 0.910 |
| Lactobacillaceae | 0.037 | 0.788 | 0.910 |
| Oscillospiraceae | 0.032 | 0.850 | 0.910 |
| Eubacterium_coprostanoligenes_group | -0.040 | 0.854 | 0.910 |
| Anaerovoracaceae | 0.094 | 0.708 | 0.910 |
| Peptostreptococcaceae | -0.057 | 0.810 | 0.910 |
| Akkermansiaceae | -0.105 | 0.819 | 0.910 |
| Peptococcaceae | 0.031 | 0.890 | 0.928 |
| Eggerthellaceae | -0.007 | 0.970 | 0.991 |
| Clostridia_UCG014 | -0.001 | 0.997 | 0.997 |
Comparison of Taxonomy
Comparison of Taxonomy
| coef (non-PD) | pval | qval | |
|---|---|---|---|
| Rhodospirillales | 0.732 | 0.004 | 0.131 |
| Monoglobales | -0.504 | 0.033 | 0.283 |
| Fusobacteriales | 0.364 | 0.027 | 0.283 |
| Pasteurellales | 0.452 | 0.038 | 0.283 |
| Lachnospirales | -0.148 | 0.066 | 0.394 |
| Oscillospirales | -0.168 | 0.121 | 0.466 |
| Enterobacterales | 0.618 | 0.122 | 0.466 |
| Synergistales | 0.285 | 0.124 | 0.466 |
| Erysipelotrichales | -0.178 | 0.249 | 0.711 |
| Clostridia;__ | 0.191 | 0.215 | 0.711 |
| VeillonellalesSelenomonadales | 0.462 | 0.261 | 0.711 |
| Coriobacteriales | 0.188 | 0.436 | 0.750 |
| Bacteroidales | -0.077 | 0.478 | 0.750 |
| Firmicutes;__;__ | 0.049 | 0.451 | 0.750 |
| Lactobacillales | 0.257 | 0.399 | 0.750 |
| Clostridia_vadinBB60_group | -0.221 | 0.375 | 0.750 |
| Clostridiales | 0.105 | 0.481 | 0.750 |
| Acidaminococcales | -0.212 | 0.500 | 0.750 |
| Burkholderiales | 0.179 | 0.433 | 0.750 |
| Victivallales | 0.057 | 0.456 | 0.750 |
| Bifidobacteriales | 0.173 | 0.532 | 0.760 |
| Methanobacteriales | 0.058 | 0.586 | 0.761 |
| Desulfovibrionales | -0.175 | 0.608 | 0.761 |
| Christensenellales | -0.163 | 0.567 | 0.761 |
| PeptostreptococcalesTissierellales | 0.102 | 0.658 | 0.789 |
| Gastranaerophilales | -0.064 | 0.736 | 0.846 |
| Izemoplasmatales | -0.031 | 0.761 | 0.846 |
| Verrucomicrobiales | -0.109 | 0.813 | 0.871 |
| Peptococcales | 0.031 | 0.889 | 0.920 |
| Clostridia_UCG014 | -0.005 | 0.988 | 0.988 |
Comparison of Taxonomy
Comparison of Taxonomy
| coef (non-PD) | pval | qval | |
|---|---|---|---|
| Alphaproteobacteria | 0.732 | 0.004 | 0.035 |
| Gammaproteobacteria | 0.498 | 0.004 | 0.035 |
| Fusobacteriia | 0.364 | 0.027 | 0.144 |
| Clostridia | -0.129 | 0.053 | 0.214 |
| Synergistia | 0.285 | 0.124 | 0.398 |
| Actinobacteria | 0.221 | 0.421 | 0.764 |
| Coriobacteriia | 0.188 | 0.436 | 0.764 |
| Bacteroidia | -0.076 | 0.477 | 0.764 |
| Firmicutes;__ | 0.049 | 0.451 | 0.764 |
| Lentisphaeria | 0.057 | 0.457 | 0.764 |
| Methanobacteria | 0.058 | 0.586 | 0.773 |
| Desulfovibrionia | -0.175 | 0.608 | 0.773 |
| Negativicutes | 0.089 | 0.628 | 0.773 |
| Bacilli | -0.064 | 0.680 | 0.777 |
| Vampirivibrionia | -0.065 | 0.736 | 0.785 |
| Verrucomicrobiae | -0.109 | 0.812 | 0.812 |
Comparison of Taxonomy
Comparison of Taxonomy
| coef (non-PD) | pval | qval | |
|---|---|---|---|
| Proteobacteria | 0.630 | 0.000 | 0.000 |
| Fusobacteriota | 0.364 | 0.027 | 0.135 |
| Firmicutes | -0.100 | 0.111 | 0.311 |
| Synergistota | 0.285 | 0.124 | 0.311 |
| Euryarchaeota | 0.058 | 0.586 | 0.760 |
| Actinobacteriota | 0.183 | 0.476 | 0.760 |
| Bacteroidota | -0.076 | 0.477 | 0.760 |
| Desulfobacterota | -0.175 | 0.608 | 0.760 |
| Cyanobacteria | -0.065 | 0.736 | 0.818 |
| Verrucomicrobiota | -0.036 | 0.935 | 0.935 |
Comparison of Taxonomy
Comparison of each KEGG Pathway
| KEGG Pathway | Pathview | coef (non-PD) | pval | qval | |
|---|---|---|---|---|---|
| ko00030 | Pentose phosphate pathway | -0.019 | 0.033 | 0.454 | |
| ko00130 | Ubiquinone and other terpenoid-quinone biosynthesis | 0.090 | 0.021 | 0.454 | |
| ko00280 | Valine, leucine and isoleucine degradation | 0.042 | 0.016 | 0.454 | |
| ko00310 | Lysine degradation | 0.048 | 0.006 | 0.454 | |
| ko00410 | beta-Alanine metabolism | 0.103 | 0.016 | 0.454 | |
| ko00480 | Glutathione metabolism | 0.047 | 0.008 | 0.454 | |
| ko00500 | Starch and sucrose metabolism | -0.031 | 0.027 | 0.454 | |
| ko00627 | Aminobenzoate degradation | 0.055 | 0.038 | 0.454 | |
| ko00710 | Carbon fixation in photosynthetic organisms | -0.012 | 0.026 | 0.454 | |
| ko00930 | Caprolactam degradation | 0.609 | 0.040 | 0.454 | |
| ko00960 | Tropane, piperidine and pyridine alkaloid biosynthesis | 0.125 | 0.034 | 0.454 | |
| ko00983 | Drug metabolism - other enzymes | 0.085 | 0.042 | 0.454 | |
| ko03040 | Spliceosome | 0.678 | 0.011 | 0.454 | |
| ko00340 | Histidine metabolism | -0.019 | 0.045 | 0.457 | |
| ko00906 | Carotenoid biosynthesis | 0.375 | 0.062 | 0.587 | |
| ko00250 | Alanine, aspartate and glutamate metabolism | -0.012 | 0.081 | 0.656 | |
| ko00521 | Streptomycin biosynthesis | -0.020 | 0.098 | 0.656 | |
| ko01051 | Biosynthesis of ansamycins | -0.035 | 0.105 | 0.656 | |
| ko03013 | RNA transport | -0.039 | 0.081 | 0.656 | |
| ko03020 | RNA polymerase | -0.028 | 0.095 | 0.656 | |
| ko05131 | Shigellosis | 0.660 | 0.098 | 0.656 | |
| ko05142 | Chagas disease | 0.403 | 0.106 | 0.656 | |
| ko05150 | Staphylococcus aureus infection | 0.327 | 0.107 | 0.656 | |
| ko00052 | Galactose metabolism | -0.022 | 0.155 | 0.805 | |
| ko00270 | Cysteine and methionine metabolism | -0.013 | 0.181 | 0.805 | |
| ko00650 | Butanoate metabolism | 0.013 | 0.168 | 0.805 | |
| ko00730 | Thiamine metabolism | -0.014 | 0.169 | 0.805 | |
| ko00791 | Atrazine degradation | 0.216 | 0.181 | 0.805 | |
| ko03015 | mRNA surveillance pathway | 0.329 | 0.163 | 0.805 | |
| ko04122 | Sulfur relay system | -0.022 | 0.183 | 0.805 | |
| ko05100 | Bacterial invasion of epithelial cells | 0.494 | 0.175 | 0.805 | |
| ko05110 | Vibrio cholerae infection | 0.187 | 0.156 | 0.805 | |
| ko00071 | Fatty acid degradation | 0.011 | 0.198 | 0.845 | |
| ko00920 | Sulfur metabolism | -0.014 | 0.206 | 0.856 | |
| ko00010 | Glycolysis / Gluconeogenesis | -0.007 | 0.311 | 0.861 | |
| ko00040 | Pentose and glucuronate interconversions | -0.025 | 0.304 | 0.861 | |
| ko00051 | Fructose and mannose metabolism | -0.011 | 0.261 | 0.861 | |
| ko00072 | Synthesis and degradation of ketone bodies | 0.062 | 0.340 | 0.861 | |
| ko00120 | Primary bile acid biosynthesis | -0.054 | 0.289 | 0.861 | |
| ko00121 | Secondary bile acid biosynthesis | -0.054 | 0.289 | 0.861 | |
| ko00260 | Glycine, serine and threonine metabolism | 0.005 | 0.309 | 0.861 | |
| ko00300 | Lysine biosynthesis | -0.012 | 0.270 | 0.861 | |
| ko00400 | Phenylalanine, tyrosine and tryptophan biosynthesis | -0.006 | 0.367 | 0.861 | |
| ko00440 | Phosphonate and phosphinate metabolism | 0.034 | 0.302 | 0.861 | |
| ko00450 | Selenocompound metabolism | -0.004 | 0.303 | 0.861 | |
| ko00472 | D-Arginine and D-ornithine metabolism | 0.099 | 0.292 | 0.861 | |
| ko00520 | Amino sugar and nucleotide sugar metabolism | -0.010 | 0.322 | 0.861 | |
| ko00540 | Lipopolysaccharide biosynthesis | 0.040 | 0.320 | 0.861 | |
| ko00591 | Linoleic acid metabolism | 0.042 | 0.334 | 0.861 | |
| ko00626 | Naphthalene degradation | 0.040 | 0.355 | 0.861 | |
| ko00633 | Nitrotoluene degradation | 0.056 | 0.246 | 0.861 | |
| ko00640 | Propanoate metabolism | 0.052 | 0.253 | 0.861 | |
| ko00760 | Nicotinate and nicotinamide metabolism | -0.007 | 0.332 | 0.861 | |
| ko00785 | Lipoic acid metabolism | 0.058 | 0.224 | 0.861 | |
| ko00860 | Porphyrin and chlorophyll metabolism | -0.015 | 0.357 | 0.861 | |
| ko01053 | Biosynthesis of siderophore group nonribosomal peptides | 0.104 | 0.325 | 0.861 | |
| ko02030 | Bacterial chemotaxis | -0.047 | 0.363 | 0.861 | |
| ko03050 | Proteasome | 0.340 | 0.269 | 0.861 | |
| ko03070 | Bacterial secretion system | 0.010 | 0.363 | 0.861 | |
| ko05111 | Biofilm formation - Vibrio cholerae | 0.078 | 0.247 | 0.861 | |
| ko00020 | Citrate cycle (TCA cycle) | 0.013 | 0.413 | 0.883 | |
| ko00620 | Pyruvate metabolism | -0.005 | 0.408 | 0.883 | |
| ko00670 | One carbon pool by folate | -0.004 | 0.389 | 0.883 | |
| ko02040 | Flagellar assembly | -0.060 | 0.392 | 0.883 | |
| ko04144 | Endocytosis | 0.197 | 0.397 | 0.883 | |
| ko05120 | Epithelial cell signaling in Helicobacter pylori infection | -0.011 | 0.406 | 0.883 | |
| ko00140 | Steroid hormone biosynthesis | 0.045 | 0.473 | 0.884 | |
| ko00240 | Pyrimidine metabolism | -0.006 | 0.485 | 0.884 | |
| ko00350 | Tyrosine metabolism | -0.007 | 0.459 | 0.884 | |
| ko00430 | Taurine and hypotaurine metabolism | 0.025 | 0.479 | 0.884 | |
| ko00471 | D-Glutamine and D-glutamate metabolism | -0.007 | 0.432 | 0.884 | |
| ko00523 | Polyketide sugar unit biosynthesis | -0.040 | 0.421 | 0.884 | |
| ko00550 | Peptidoglycan biosynthesis | -0.010 | 0.449 | 0.884 | |
| ko00561 | Glycerolipid metabolism | -0.014 | 0.481 | 0.884 | |
| ko00562 | Inositol phosphate metabolism | -0.011 | 0.489 | 0.884 | |
| ko00600 | Sphingolipid metabolism | -0.030 | 0.470 | 0.884 | |
| ko02020 | Two-component system | 0.014 | 0.434 | 0.884 | |
| ko03008 | Ribosome biogenesis in eukaryotes | 0.012 | 0.446 | 0.884 | |
| ko03018 | RNA degradation | 0.004 | 0.497 | 0.887 | |
| ko01055 | Biosynthesis of vancomycin group antibiotics | 0.009 | 0.509 | 0.896 | |
| ko00680 | Methane metabolism | -0.005 | 0.558 | 0.910 | |
| ko00790 | Folate biosynthesis | 0.011 | 0.539 | 0.910 | |
| ko00908 | Zeatin biosynthesis | -0.007 | 0.560 | 0.910 | |
| ko03022 | Basal transcription factors | 0.066 | 0.554 | 0.910 | |
| ko03060 | Protein export | 0.003 | 0.564 | 0.910 | |
| ko04626 | Plant-pathogen interaction | -0.009 | 0.560 | 0.910 | |
| ko04974 | Protein digestion and absorption | -0.054 | 0.568 | 0.910 | |
| ko05012 | Parkinson disease | 0.210 | 0.551 | 0.910 | |
| ko00510 | N-Glycan biosynthesis | -0.015 | 0.606 | 0.910 | |
| ko00531 | Glycosaminoglycan degradation | 0.033 | 0.607 | 0.910 | |
| ko00750 | Vitamin B6 metabolism | -0.006 | 0.584 | 0.910 | |
| ko03420 | Nucleotide excision repair | -0.005 | 0.583 | 0.910 | |
| ko04146 | Peroxisome | 0.012 | 0.600 | 0.910 | |
| ko05410 | Hypertrophic cardiomyopathy | 0.152 | 0.604 | 0.910 | |
| ko00053 | Ascorbate and aldarate metabolism | 0.008 | 0.725 | 0.923 | |
| ko00061 | Fatty acid biosynthesis | -0.004 | 0.707 | 0.923 | |
| ko00230 | Purine metabolism | -0.003 | 0.701 | 0.923 | |
| ko00290 | Valine, leucine and isoleucine biosynthesis | -0.005 | 0.685 | 0.923 | |
| ko00473 | D-Alanine metabolism | 0.006 | 0.718 | 0.923 | |
| ko00601 | Glycosphingolipid biosynthesis - lacto and neolacto series | 0.108 | 0.685 | 0.923 | |
| ko00660 | C5-Branched dibasic acid metabolism | 0.006 | 0.688 | 0.923 | |
| ko00720 | Carbon fixation pathways in prokaryotes | 0.005 | 0.677 | 0.923 | |
| ko00740 | Riboflavin metabolism | -0.004 | 0.692 | 0.923 | |
| ko00780 | Biotin metabolism | 0.009 | 0.645 | 0.923 | |
| ko00941 | Flavonoid biosynthesis | -0.063 | 0.655 | 0.923 | |
| ko01040 | Biosynthesis of unsaturated fatty acids | 0.008 | 0.662 | 0.923 | |
| ko02010 | ABC transporters | 0.011 | 0.656 | 0.923 | |
| ko02060 | Phosphotransferase system (PTS) | -0.027 | 0.654 | 0.923 | |
| ko03440 | Homologous recombination | -0.003 | 0.726 | 0.923 | |
| ko03450 | Non-homologous end-joining | 0.045 | 0.725 | 0.923 | |
| ko04075 | Plant hormone signal transduction | 0.122 | 0.633 | 0.923 | |
| ko00100 | Steroid biosynthesis | -0.127 | 0.795 | 0.931 | |
| ko01501 | beta-Lactam resistance | -0.018 | 0.815 | 0.931 | |
| ko00330 | Arginine and proline metabolism | -0.001 | 0.786 | 0.931 | |
| ko00361 | Chlorocyclohexane and chlorobenzene degradation | -0.015 | 0.789 | 0.931 | |
| ko00564 | Glycerophospholipid metabolism | 0.003 | 0.753 | 0.931 | |
| ko00770 | Pantothenate and CoA biosynthesis | -0.002 | 0.776 | 0.931 | |
| ko00830 | Retinol metabolism | -0.031 | 0.792 | 0.931 | |
| ko00900 | Terpenoid backbone biosynthesis | -0.003 | 0.782 | 0.931 | |
| ko03010 | Ribosome | -0.003 | 0.818 | 0.931 | |
| ko03430 | Mismatch repair | -0.002 | 0.803 | 0.931 | |
| ko04112 | Cell cycle - Caulobacter | -0.002 | 0.810 | 0.931 | |
| ko04621 | NOD-like receptor signaling pathway | 0.005 | 0.792 | 0.931 | |
| ko05146 | Amoebiasis | -0.015 | 0.802 | 0.931 | |
| ko03030 | DNA replication | 0.002 | 0.829 | 0.935 | |
| ko00311 | Penicillin and cephalosporin biosynthesis | -0.017 | 0.839 | 0.937 | |
| ko00970 | Aminoacyl-tRNA biosynthesis | -0.003 | 0.851 | 0.937 | |
| ko04210 | Apoptosis | -0.015 | 0.851 | 0.937 | |
| ko00630 | Glyoxylate and dicarboxylate metabolism | 0.001 | 0.858 | 0.938 | |
| ko03410 | Base excision repair | 0.001 | 0.869 | 0.943 | |
| ko00514 | Other types of O-glycan biosynthesis | 0.037 | 0.883 | 0.950 | |
| ko00362 | Benzoate degradation | 0.003 | 0.891 | 0.952 | |
| ko00281 | Geraniol degradation | -0.007 | 0.950 | 0.975 | |
| ko00380 | Tryptophan metabolism | 0.006 | 0.937 | 0.975 | |
| ko00511 | Other glycan degradation | -0.002 | 0.961 | 0.975 | |
| ko00910 | Nitrogen metabolism | 0.001 | 0.958 | 0.975 | |
| ko04141 | Protein processing in endoplasmic reticulum | -0.002 | 0.922 | 0.975 | |
| ko04910 | Insulin signaling pathway | 0.001 | 0.949 | 0.975 | |
| ko05143 | African trypanosomiasis | -0.014 | 0.949 | 0.975 | |
| ko00190 | Oxidative phosphorylation | -0.000 | 0.984 | 0.990 | |
| ko00360 | Phenylalanine metabolism | -0.000 | 0.990 | 0.990 |
Comparison of each KEGG Pathway
Shape
Gram stain
Oxygen requirement
Sporulation
Motility
© 2022 Division of Translational Informatics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center